Guat Bee Tan

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We established a normal reference range for peripheral blood lymphocyte subsets in a multiracial adult population by using single-platform flow cytometry. Further analysis of our cohort showed that the CD8+-cell counts decrease with age, there is a gender difference in NK cell percentages and counts, and there are significant differences in the CD3+-,(More)
Tuberculosis is the most common opportunistic infection in HIV-infected people living in developing countries and is believed to accelerate the progression of HIV disease. This effect may be mediated by increased immune activation. We measured levels of CD4 and CD8 T-lymphocyte activation and proliferation in control subjects, patients with HIV alone, TB(More)
The accumulation of toxic or otherwise harmful trace gases in a spacecraft cabin is a very serious concern in terms of the health and safety of the crew. Although methods exist for controlling the evolution of such contaminants, techniques for monitoring the success of these methods, on board and in near- real-time, are still under development. One such(More)
Following an enthusiastic start in 1985, ESA's life support technology development programme was re-assessed in the mid- to late-1990s to reflect the strong reduction in European manned space ambitions which occurred at that time. Further development was essentially restricted to activities that could constitute ISS upgrades or enhancements, or support ISS(More)
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