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The purpose of the present study is to identify whether interleukin (IL)-18 can modulate cysteinyl leukotriene 2 receptor (CysLT2R) expression in Human Umbilical Vein Endothelial Cells (HUVECs) and how it influences the cell death. According to the results from real-time reverse transcription PCR, confocal laser scanning microscopy, and western blotting, a(More)
Atherosclerosis is characterized by inflammatory responses of the arterial wall to "injury", which is prominently driven by inflammatory mediators. Montelukast, a selective CysLT1 receptor antagonist, has potent anti-inflammatory effects in diverse animal models. However, the role of montelukast in regulating inflammatory progression of atherosclerosis has(More)
BACKGROUND Low socioeconomic status (SES) is associated with increased mortality after stroke in developed countries. This study was performed to determine whether a similar association also exists in China. METHODS A total of 806 patients with first-ever ischemic stroke were enrolled in our study. From August 1999 to August 2005, the three-year all-cause(More)
OBJECTIVE The 5-lipoxygenase catalyzed formation of leukotriene lipid mediators is a mediator for inflammatory response in arteries. The present study investigated the relationship between atorvastatin and the 5-lipoxygenase pathway in an atherosclerotic rabbit model. METHODS Thirty male New Zealand White Rabbits were randomized into negative control,(More)
Hyperperfusion syndrome is a well-documented clinical complication after endarterectomy and carotid stenting. However, little is known about this complication immediately after vertebral artery stenting. A 51-year-old woman who had repeated episodes of dizziness, nausea, and vomiting was diagnosed with vertebrobasilar insufficiency. Diffusion-weighted(More)
—In this letter, an unsupervised method for estimating the equivalent number of looks (ENL) in synthetic aperture radar (SAR) images is proposed. Assuming that the multiplicative noise in the SAR images is a unit mean random variable of Gamma distribution parameterized by the ENL, a lookup table between the ENL and the variance of the logarithm of the(More)
BACKGROUND Matrix metalloproteinases (MMPs) play important roles in the development and destabilization of atherosclerotic plaques. It is known that montelukast inhibits neointimal hyperplasia. However, the underlying mechanisms for the inhibitory effects of montelukast on neointimal formation have been poorly defined. METHODS Thirty-six male New Zealand(More)
SUMMARY In this paper, a new method is proposed for unsupervised speckle level estimation in synthetic aperture radar (SAR) images. It is assumed that fully developed speckle intensity has a Gamma distribution. Based on this assumption, estimation of the equivalent number of looks (ENL) is transformed into noise variance estimation in the logarithmic SAR(More)