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Curcumin Modulates the Inflammatory Response and Inhibits Subsequent Fibrosis in a Mouse Model of Viral-induced Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome (ARDS) is a clinical syndrome characterized by diffuse alveolar damage usually secondary to an intense host inflammatory response of the lung to a pulmonary orExpand
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Human Metapneumovirus M2-2 Protein Inhibits Innate Immune Response in Monocyte-Derived Dendritic Cells
Human metapneumovirus (hMPV) is a leading cause of lower respiratory infection in young children, the elderly and immunocompromised patients. Repeated hMPV infections occur throughout life. However,Expand
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The in vitro immunomodulatory activity of a polysaccharide isolated from Kadsura marmorata.
Kadsura marmorata has been used in traditional Chinese medicine as one of the major ingredients for the treatment of bronchial asthma, eczema, and acute and chronic infection due to either viruses orExpand
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Protective MCMV immunity by vaccination of the salivary gland via Wharton's duct: replication‐deficient recombinant adenovirus expressing individual MCMV genes elicits protection similar to that of
Salivary glands, a major component of the mucosal immune system, confer antigen‐specific immunity to mucosally acquired pathogens. We investigated whether a physiological route of inoculation and aExpand
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Differential Response of First-Order Lateral Root Elongation to Low Potassium Involves Nitric Oxide in Two Tobacco Cultivars
Potassium (K+) is a major limiting element of plant growth, and crops often suffer from low-K+ (LK) stress. Although nitric oxide (NO) is a signaling molecule involved in plant root adaptation to theExpand
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Exploring voluntary vaccination with bounded rationality through reinforcement learning
Abstract Evidence shows that there exists a complex interaction between human vaccinating behaviors and disease prevalence during an epidemic. Usually, rational individuals make vaccinating decisionsExpand
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Salivary gland immunization via Wharton's duct activates differential T‐cell responses within the salivary gland immune system
Salivary glands are a major component of the mucosal immune system that confer adaptive immunity to mucosal pathogens. As previously demonstrated, immunization of the submandibular gland with tissueExpand
Perfluorooctanesulfonate Induces Hepatomegaly and Lipoatrophy in Mice through Phosphoenolpyruvate Carboxykinase-Mediated Glyceroneogenesis Inhibition
Perfluorooctansulfonate (PFOS) is a persistent organic pollutant that has attracted a great deal of attention due to toxic effects such as its lipid metabolism-disrupting potential. Exposure to PFOSExpand
Inhibitory effect of peripheral blood iTr35 cells on vascular endothelial cell vascular cell adhesion molecule-1 in children with pulmonary artery hypertension
Objective To explore the role of iTr35 cells in the pathogenesis of children with pulmonary artery hypertension (PAH) in children, and the percentage of iTr35 cells and serum interleukin(IL)-35Expand
Interleukin-35 sensitizes monocytes from patients with asthma to glucocorticoid therapy by regulating p38 MAPK
The activation of monocytes and macrophages is associated with steroid-resistant (SR) asthma. Interleukin-35 (IL-35) is an important anti-inflammatory cytokine, but its regulatory effects onExpand