Guangjin Li

Jörg J. Goronzy3
Cornelia M. Weyand3
3Jörg J. Goronzy
3Cornelia M. Weyand
2Won-Woo Lee
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The ability of the human immune system to respond to vaccination declines with age. We identified an age-associated defect in T cell receptor (TCR)-induced extracellular signal-regulated kinase (ERK) phosphorylation in naive CD4(+) T cells, whereas other signals, such as ζ chain-associated protein kinase 70 (ZAP70) and phospholipase C-γ1 phosphorylation,(More)
Immune aging is best known for its immune defects that increase susceptibility to infections and reduce adaptive immune responses to vaccination. In parallel, the aged immune system is prone to autoimmune responses and many autoimmune diseases increase in incidence with age or are even preferentially encountered in the elderly. Why an immune system that(More)
Zinc is a trace element that is essential for innate and adaptive immune responses. In addition to being a structural element of many proteins, zinc also functions as a neurotransmitter and an intracellular messenger. Temporal or spatial changes in bioavailable zinc may influence the activity of several enzymes, including kinases and phosphatases. We(More)
I. ABSTRACT This paper presents a fast and precise electromagnetic-thermal model of a redundant dual star Flux-Switching Permanent Magnet (FSPM) motor for the embedded applications with driving cycles, e.g. Hybrid Electrical Vehicle (HEV), aerospace, etc. This model is based on a prior steady characterization by Finite Element Method (FEM) 2D of the FSPM(More)
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