Guang-xue Chen

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Genetic factors are known to be important in the development of esophageal squamous cell carcinoma (ESCC). Epidermal growth factor (EGF) can activate several signaling pathways leading to proliferation, differentiation, and tumorigenesis of epithelial tissues by binding with its receptor. Interindividual variations in EGF production were genetically(More)
Spatial data mining is the process of identifying or extracting efficient, novel, potentially useful and ultimately understandable patterns from the spatial data set, the spatial clustering analysis is one of the most important research directions in spatial data mining. Clustering criterion implied in massive data can be discovered by spatial clustering(More)
OBJECTIVE To explore the role of phospholipase C-gamma1 (PLC-gamma1) signaling pathway in H(2)O(2)-induced apoptosis of PC12 cells. METHODS PC12 cells were exposed to 50 micromol/L H(2)O(2) after pretreatment with 10 micromol/L U73122, a specific PLC-gamma1 inhibitor. Hoechst/PI double staining was performed to observe the morphological changes of the(More)
The reasons of Moiré Fringe of halftone image were analyzed and the rules of Moiré Fringe distribution, e.g., the screening frequency influence on Moiré Fringe and the screening angle influence on the amplitudes and shapes of Moiré Fringe, were studied in this paper. One method to avoid Moiré Fringe great influence on(More)
We report the application of modified pulse-coupled neural network (PCNN) models as an image processing tool to improve the quality of digital halftoning. Four factors including weight matrice, internal activity computation, type of error diffusion and linking coefficient were researched and optimized in terms of the PSNR metric and visual inspection on(More)
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