Guang-mei Li

Learn More
The purpose of this investigation was to elucidate the organization of efferent neurons in the mesocerebrum of a terrestrial snail. The mesocerebrum is one of three regions, or lobes, that can be identified by gross inspection. Previous studies have indicated a possible function for the mesocerebrum in the control of mating behavior. We used both(More)
Arachidonic acid (AA), 5,8,11,14-eicosateraenoic acid is abundant, active and necessary in the human body. In the present study, we reported the neuroprotective effects and mechanism of arachidonic acid on hippocampal slices insulted by glutamate, NaN(3) or H(2)O(2)in vitro. Different types of models of brain injury in vitro were developed by 1mM glutamate,(More)
AIM To observe the effects of stearic acid, a long-chain saturated fatty acid consisting of 18 carbon atoms, on brain (cortical or hippocampal) slices insulted by oxygen-glucose deprivation (OGD), glutamate or sodium azide (NaN3) in vitro. METHODS The activities of hippocampal slices were monitored by population spikes recorded in the CA1 region. In vitro(More)
AIM To observe the effects of stearic acid against oxidative stress in primary cultured cortical neurons. METHODS Cortical neurons were exposed to glutamate, hydrogen peroxide (H2O2), or NaN3 insult in the presence or absence of stearic acid. Cell viability of cortical neurons was determined by MTT assay and LDH release. Endogenous antioxidant enzymes(More)
Stearic acid is a long-chain saturated fatty acid consisting of 18 carbon atoms without double bonds. In the present study, we reported the neuroprotective effects and mechanism of stearic acid on cortical or hippocampal slices insulted by oxygen-glucose deprivation, NMDA or hydrogen peroxide (H(2)O(2)) in vitro. Different types of models of brain slice(More)
  • 1