Guang-jie Xie

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OBJECTIVE To characterize the acute and chronic behavioral, electrographic and histological changes of sustained seizures induced by pilocarpine in rats. METHODS The rats in the study were divided into the experimental group and control group. After status epilepticus (SE) was induced in the experimental rats, the surviving animals were continuously(More)
Chronic lead exposure during brain development is known to affect cognitive and behavioral functions in children and animals. The lead exposure on pregnant rats was used as a model to examine the effects of lead on the long-term potentiation(LTP) in hippocampal dentate gyrus(DG) region in vivo and the expression of NMDAR-2A mRNA by in situ hybridization in(More)
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