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OBJECTIVE To characterize the acute and chronic behavioral, electrographic and histological changes of sustained seizures induced by pilocarpine in rats. METHODS The rats in the study were divided into the experimental group and control group. After status epilepticus (SE) was induced in the experimental rats, the surviving animals were continuously(More)
OBJECTIVE To observe the kindling model of Sprague-Dawley (SD) rats induced by injection of different doses of picrotoxin (PTX) intraperitoneally, and to evaluate the effect of the drug on the model. METHODS SD rats were devided randomly into four groups: control group, epilepsy Group I (PTX, 1.5 mg.kg-1.d-1), epilepsy Group II (PTX, 2 mg.kg-1.d-1) and(More)
  • G J Xie
  • 1990
In 6 cases of polymyositis was performed muscle and sural nerve biopsy. All the 6 patients presented typical clinical pictures of simple polymyositis. Sural nerves showed demyelination and axonal changes, under light and electron microscopy. It seems that simple polymyositis accompanied by the alterations in peripheral nerves is not very rare. In 3 cases, a(More)
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