Guang-fu Dong

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OBJECTIVE To acquire more knowledge about neonatal lupus erythematosus (NLE). METHOD Seven cases with neonatal lupus erythematosus who were seen in this hospital from 1990 to 2009 are reported in this paper and 87 cases reported previously from 1980 to now in China were reviewed. The clinical manifestations, serum autoantibodies, treatment and results of(More)
OBJECTIVE To understand the prevalence, investigate the correlation of clinical features, explore the early-stage diagnosis and treatment of pulmonary arterial hypertension (PAH) in patients with connective tissue disease (CTD). METHODS All cases with pulmonary arterial hypertension in 1892 CTD patients were analyzed retrospectively. The risk factor of(More)
It is known that the organic molecules can provide an effective means to manipulate the surface properties of the biodegradable ceramic. There are two ways to modify the surface of the biodegradable ceramic by organic molecules. The first one is through surface adsorption but organic molecules will easily be washed out in the physiological environment. The(More)
OBJECTIVE To compare the efficacy of transplanting bone marrow mesenchymal stem cell (BMSC) or microenvironmental induced BMSC (iBMSC) into the ischemic myocardium of rats with myocardial infarction. METHODS iBMSC was defined as BMSC co-cultured with myocardial cells for 2 weeks. The stem cells or equal volume PBS were injected into ischemic border zone 1(More)
OBJECTIVE To detect the effects of leflunomide to phenotype and function of dendritic cells (DCs) in systemic lupus erythematosus (SLE) patients, reveal the effective mechanism inducing remission of SLE and lay a research foundation for using 'inhibit' DCs to treat SLE in future. METHODS The monocytes were isolated from peripheral blood of SLE patients(More)
Investigating for interior regularity of viscosity solutions to the fully nonlinear elliptic equation F (x, u,▽u,▽u) = 0, we establish the interior C continuity under the assumptions that F is uniformly elliptic, Hölder continuous and satisfies the natural structure conditions of fractional order, but without the concavity assumption of F . These(More)
OBJECTIVE To discuss whether PP-2A influences the phosphorylation level at APP threonine 668 locus thus regulating Aβ secretion. METHOD In the experiment, 24 hours after N2a cells of stably transfected human APP (N2a/APP) were treated with okadaic acid (OA) or DES (C6-ceramide) (N2a/APP), an injection of OA cerebral stereotactic was administered to a SD(More)