Guang Zhang

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The authors thank the editor, the associate editor, and two reviewers for their helpful comments and suggestions which led to a much improved presentation. Taylor & Francis makes every effort to ensure the accuracy of all the information (the " Content ") contained in the publications on our platform. However, Taylor & Francis, our agents, and our licensors(More)
Background. Hepatocellular carcinoma (HCC) represents the sixth common cancer in the world. Single nucleotide polymorphisms (SNPs) in microRNA genes may be associated with susceptibility to HCC. Recently, several studies have reported possible associations of SNPs miR-499 T>C rs3746444 and miR-34b/c T>C rs4938723 with the risk of HCC. However the results(More)
BACKGROUND Hepatocellular carcinoma (HCC) remains a disastrous disease and the treatment for HCC is rather limited. Separation and identification of active compounds from traditionally used herbs in HCC treatment may shed light on novel therapeutic drugs for HCC. METHODS Cell viability and colony forming assay were conducted to determine anti-HCC(More)
Low power CMOS DTV tuner is strongly needed for current DTV receiver. Conventional tuner solution is based on Bipolar or BiCMOS technology. Furthermore many off-chip components are necessary needed. In this project, we will try to implement a low power, SAW-less, CMOS DTV tuner. To demonstrate the idea, key blocks of tuner like VGA and mixer and frequency(More)
Online auctions are one of the most effective ways of negotiation of salable goods over the internet. Software agents are increasingly being used to represent humans in online auctions. These agents can systematically monitor a wide variety of auctions and can make rapid decisions about what bids to place in what auctions. To be successful in open(More)
Background. Despite improvement in treatment, the prognosis of hepatocellular carcinoma (HCC) remains disastrous. Cancer stem cells (CSCs) may be responsible for cancer malignant behaviors. ATP-binding cassette, subfamily G, member 2 (ABCG2) is widely expressed in both normal and cancer stem cells and may play an important role in cancer malignant(More)
The Sonic Hedgehog (Shh) pathway affects cancer initiation, progression, and metastasis, but its role in papillary thyroid carcinoma (PTC) remains elusive. To characterize expression and clinical significance of Shh and the transcription factor Gli-1—the key elements of the Shh pathway in PTC tissues—we immunohistochemically examined Shh/Gli-1 expression in(More)
PURPOSE Tumor microenvironment confers drug resistance to kinase inhibitors by increasing RKT ligand levels that result in the activation of cell-survival signaling including PI3K and MAPK signals. We assessed whether HSC-LX2 coculture conferred sorafenib resistance in Huh7 and revealed the mechanism underlying the drug resistance. EXPERIMENTAL DESIGN The(More)