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The number of studies focused on the transformation and sequestration of soil organic carbon (C) has dramatically increased in recent years due to growing interest in understanding the global C cycle. While it is readily accepted that terrestrial C dynamics are heavily influenced by the catabolic and anabolic activities of microorganisms, the incorporation(More)
A study on correlation between structure and resistivity variations was performed for live adult human skull. The resistivities of 388 skull samples, excised from 48 skull flaps of patients undergoing surgery, were measured at body temperature (36.5 degrees C) using the well-known four-electrode method in the frequency range of 1-4 MHz. According to(More)
Serotonergic receptors take their physiologic effects by affecting adenylyl cyclase (AC) catalytic activity and cyclic adenosine monophosphate (cAMP) concentration. AC-cAMP second messenger pathway has been recently suggested to play an important role in depression. Therefore, the compound that regulates the signal pathway may have potential as(More)
Partially linear models provide a useful class of tools for modeling complex data by naturally incorporating a combination of linear and nonlinear effects within one framework. One key question in partially linear models is the choice of model structure, that is, how to decide which covariates are linear and which are nonlinear. This is a fundamental, yet(More)
We consider higher order frequentist inference for the parametric component of a semiparametric model based on sampling from the posterior profile distribution. The first order validity of this procedure established by Lee, Kosorok and Fine in [J. American Statist. Assoc. 100 (2005) 960– 969] is extended to second-order validity in the setting where the(More)
We consider the estimation of sparse graphical models that characterize the dependency structure of high-dimensional tensor-valued data. To facilitate the estimation of the precision matrix corresponding to each way of the tensor, we assume the data follow a tensor normal distribution whose covariance has a Kronecker product structure. The penalized maximum(More)
A common practice in obtaining an efficient semiparametric estimate is through iteratively maximizing the (penalized) full log-likelihood w.r.t. its Euclidean parameter and functional nuisance parameter. A rigorous theoretical study of this semiparametric iterative estimation approach is the main purpose of this paper. We first show that the grid search(More)
We consider the efficient estimation in the semiparametric additive isotonic regression model where each additive nonparametric component is assumed to be a monotone function. We show that the least-square estimator of the finite-dimensional regression coefficient is root-n consistent and asymptotically normal. Moreover, the isotonic estimator of each(More)
14-3-3 proteins have attracted much recent interest in the etiopathogenesis of human cancers owing to their involvement in the prevention of apoptosis. However, the expression of 14-3-3 in primary nervous system tumors has not been previously characterized. In this paper, Immunohistochemistry using a specific anti-14-3-3 antibody was performed on(More)