Guan Zhang

Learn More
OBJECTIVE Published studies have yielded inconsistent results on the relationship between p53 status and the prognosis of non-muscle invasive bladder cancer (NMIBC) treated with Bacillus Calmette-Guérin (BCG) intravesical therapy. Therefore, we performed a meta-analysis to evaluate the prognostic value of p53 in NMIBC treated with BCG. METHODS We(More)
Perturbations in cell cycle and DNA repair genes might affect susceptibility to cancer. The aim of this meta-analysis is to generate large-scale evidence to determine the degree to which common Cyclin D1 (CCND1) G870A (dbSNP: rs603965) and xeroderma pigmentosum group C (XPC) Ala499Val (dbSNP: rs2228000) polymorphisms are associated with susceptibility to(More)
It is well known that neurogenesis is not the only concern for the fully functional recovery after brain or spinal cord injury, as it has been shed light on the critical role of angiogenesis in improving neurological functional recovery. Angiogenesis and neurogenesis coordinately interact with each other in the developing and adult brain, during which they(More)
The trench performance of UMOS is very important because it directly affects chip performance. This paper reveals that, during the HTGB test, the trench MOS gate device is seriously degraded due to poor trench uniformity and sidewall profile. In addition, for ultra thick gate oxide (about 500A), the GOI Vramp criteria should be revised.
High temperature is a rigorous environment factor for reliability tests in automotive IC evaluations. In this paper, we study Isub with Vds stress correlation at different temperatures, and propose a quadratic fit between Isub and Vds stress. The HCI (Hot Carrier Injection) lifetime is studied for temperature dependence at the same time.
With the introduction of new material (e.g., ultra-low-K inter-metal dielectrics) and package technology (e.g., laser grooving), there are new challenges on product reliability, especially on environmental stress tests related to film adhesion. To better understand the impacts of these changes on field applications, a new evaluation method, the die pull(More)
OBJECTIVES Based on the important changes in South Africa since 2009 and the Antiretroviral Treatment Guideline 2013 recommendations, we explored the cost-effectiveness of different strategy combinations according to the South African HIV-infected mothers' prompt treatments and different feeding patterns. STUDY DESIGN A decision analytic model was applied(More)