Grzegorz Zuk

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The improved column chromatographic method has been developed for the determination of tetracycline, oxytetracycline N-pyrrolidinemethyltetracycline, methacycline, doxycycline and their degradation products (anhydro and epi forms) in pharmaceutical preparations. The analyses of 13 commercial preparations showed them to contain certain amounts of degradation(More)
Adherence to medication is one of the most significant challenges of secondary prevention in patients after an acute myocardial infarction (AMI). Indeed, it has been well established that higher adherence is associated with better cardiovascular outcomes. Research pertaining to secondary prevention after AMI treated with percutaneous coronary intervention(More)
Fractional flow reserve (FFR) is an evidence-based diagnostic tool of physiological significance of coronary artery stenosis in patients with stable coronary artery disease (CAD). Due to microvascular dysfunction in acute coronary syndrome (ACS), information obtained from FFR assessment could be less reliable and, thus, its clinical role remains(More)
The spectrophotometric method was employed for determination of tetracycline (1) and its degradation products epitetracycline (2), anhydrotetracycline (3) and anhydroepitetracycline (4). The determination has been based on the difference in the molar absorptivities (epsilon) of 1 and 2 at 254 and 267 nm, as well as of 3 and 4 at 260 and 272 nm,(More)
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