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  • Rajendra Prasad, Grigory L Dianov, Vilhelm A. Bohr, Samuel H. Wilson
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2000 (First Publication: 11 February 2000)
  • In mammalian cells, single-base lesions, such as uracil and abasic sites, appear to be repaired by at least two base excision repair (BER) subpathways: "single-nucleotide BER" requiring DNA synthesisContinue Reading
  • Grigory L Dianov, Tatyana V. Timehenko, O. I. Sinitsina, Andrew V. Kuzminov, O A Medvedev, Rudolf I. Salganik
  • Biology, Medicine
  • Molecular and General Genetics MGG
  • 2004 (First Publication: 1 March 1991)
  • SummaryThe role of closely spaced lesions on both DNA strands in the induction of double-strand breaks and formation of deletions was studied. For this purpose a polylinker sequence flanked by 165 byContinue Reading
  • Jason L. Parsons, Phillip S Tait, David Finch, Irina I. Dianova, Sarah L. Allinson, Grigory L Dianov
  • Biology, Medicine
  • Molecular cell
  • 2008 (First Publication: 1 February 2008)
  • Base excision repair (BER) is the major pathway for processing of simple lesions in DNA, including single-strand breaks, base damage, and base loss. The scaffold protein XRCC1, DNA polymerase beta,Continue Reading