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Unified rational protein engineering with sequence-based deep representation learning
- E. Alley, Grigory Khimulya, Surojit Biswas, Mohammed AlQuraishi, G. Church
- Biology, Computer ScienceNature Methods
- 21 October 2019
TLDR
EpiFactors: a comprehensive database of human epigenetic factors and complexes
- Y. Medvedeva, A. Lennartsson, F. Drabløs
- BiologyDatabase J. Biol. Databases Curation
- 7 July 2015
TLDR
Unified rational protein engineering with sequence-only deep representation learning
- E. Alley, Grigory Khimulya, Surojit Biswas, Mohammed AlQuraishi, G. Church
- Biology, Computer SciencebioRxiv
- 26 March 2019
TLDR
Low-N protein engineering with data-efficient deep learning
- Surojit Biswas, Grigory Khimulya, E. Alley, K. Esvelt, G. Church
- Biology, Computer Science
- 24 January 2020
TLDR
Low-N protein engineering with data-efficient deep learning.
- Surojit Biswas, Grigory Khimulya, E. Alley, K. Esvelt, G. Church
- BiologyNature methods
- 1 April 2021
TLDR
PERFECTOS-APE - Predicting Regulatory Functional Effect of SNPs by Approximate P-value Estimation
- I. Vorontsov, I. Kulakovskiy, Grigory Khimulya, D. Nikolaeva, V. Makeev
- BiologyBIOINFORMATICS
- 2015
Single nucleotide polymorphisms (SNPs) and variants (SNVs) are often found in regulatory regions of human genome. Nucleotide substitutions in promoter and enhancer regions may affect transcription…
Negative selection maintains transcription factor binding motifs in human cancer
- I. Vorontsov, Grigory Khimulya, V. Makeev
- BiologyBMC Genomics
- 9 November 2015
TLDR
Unified rational protein engineering with sequence-based deep representation learning
- E. Alley, Grigory Khimulya, Surojit Biswas, Mohammed AlQuraishi, G. Church
- Biology
- 20 November 2019
This protocol describes the computational steps necessary to reproduce the results described in the paper "Unified rational protein engineering with sequence-only deep representation learning" by…