Gregorz Opala

Learn More
BACKGROUND Huntington's disease (HD) is a rare triplet repeat (CAG) disorder. Advanced, multi-centre, multi-national research frameworks are needed to study simultaneously multiple complementary aspects of HD. This includes the natural history of HD, its management and the collection of clinical information and biosamples for research. METHODS We report(More)
Several candidate modifier genes which, in addition to the pathogenic CAG repeat expansion, influence the age at onset (AO) in Huntington disease (HD) have already been described. The aim of this study was to replicate association of variations in the N-methyl D-aspartate receptor subtype genes GRIN2A and GRIN2B in the "REGISTRY" cohort from the European(More)
BACKGROUND AND PURPOSE Parkinson disease (PD) is one of the most frequent diseases of the central nervous system. Rehabilitation is one of the factors which may help the patients to maintain higher physical activity in everyday life. The aim of this work was to evaluate the influence of movement rehabilitation on severity of motor symptoms in PD patients.(More)
S-adenosyl L-methionine (SAMe) is the natural, universal methyl group donor, participating in transmethylation reactions, known and commonly used as a dietary supplement since 1952. It plays an important role in the synthesis of neuromediators and melatonin and mechanisms of epigenetic regulation. The aim of this article is to review the literature about(More)
  • G Opala
  • 1991
Internal carotid loop was studied in 99 patients out of 1638 cases subjected to angiography. The presence of a loop was arbitrarily accepted when in the tortuous part of the artery one of its segments was situated below the preceding segment. For the spatial analysis of the tortuous part of the artery and its image in the plane of the radiogram a model was(More)
As part of the programme of investigations on the effect of environmental pollution, which is far advanced in the Upper Silesian Industrial Region, on the health of the population the authors analysed the death rate from vascular diseases of the central nervous system. Using the data of the Central Statistical Bureau this death rate in the years 1976-1986(More)
  • G Opala
  • 1988
In a group of 99 patients with unilateral or bilateral carotid artery loop the data in case records were analysed. In 11 cases no abnormalities were found, apart from the presence of carotid loop, that could be related to the presence of symptoms of cerebrovascular insufficiency observed in them. In 7 of them these symptoms appeared before the age of 40(More)
The authors report a case of coexistence of Eales disease and multiple sclerosis in which signs of perivenous retinitis preceded by 25 years the appearance of neurological changes. Considering the similarity in the course of both disease and the histological character of perivascular changes the authors suggest presence of a common causative factor and(More)