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Recent studies indicate that oxygen radicals such as superoxide or singlet oxygen may be important in the functional activity of human granulocytes. We have examined the possible importance of these radicals in the functional capacity of human blood monocytes. Monocytes, like granulocytes, generate chemiluminescence during phagocytosis. Chemiluminescence is(More)
This study investigated effects of step length on the stepping response used to arrest an impending forward fall. Twelve healthy young (mean age 22, S.D. 3.3 years) males participated by recovering balance with a single step following a forward lean-and-release. Participants were instructed to step to one of three floor targets representing small, natural,(More)
A number of highly reactive oxygen species have been implicated in the oxygen-dependent mechanisms involved in bactericidal activity of phagocytic leukocytes. Hydrogen peroxide and superoxide, two agents known to occur during phagocytosis, are thought to interact to generate hydroxyl radical, singlet oxygen, and other potentially reactive molecules. Using(More)
A highly pure preparation of neoplastic cells from the spleen of a patient with leukemic reticuloendotheliosis was studied for function, membrane characteristics and glucose metabolism. Glass adherence and phagocytosis of small particles (latex and carbon black) were demonstrated with phase contrast microscopy. Staphylocidal activity was similar to that of(More)
  • G W King
  • 1980
The afferent projections to nucleus parabrachialis (NPB) and nearby pontine areas from the lower brainstem were studied in cats using retrograde horseradish peoxidase (HRP) and anterograde autoradiographic tracing techniques. Two groups of medullary neurons send major projections to NPB and the Kölliker-Fuse nucleus (KF): 1) the solitary complex, especially(More)
Immunologic function was evaluated in 12 patients with Hodgkin's disease and 5 patients with lymphocytic lymphoma who had been successfully treated with either chemotherapy, radiation therapy, or both of these modalities 3-42 mo previously. Only two of the patients were found to have total anergy to a battery of six recall skin test antigens and all were(More)
OBJECTIVE The goal was to evaluate, in a clinical study, the predicted performance of the transverse tripolar system for spinal cord stimulation, particularly the steering of paresthesia, paresthesia coverage, and the therapeutic range of stimulation. METHODS Six transverse tripolar electrodes were implanted in the lower thoracic region in four patients(More)
A multicenter study was initiated to evaluate the performance of the transverse tripolar system for spinal cord stimulation. Computer modeling had predicted steering of paresthesia with a dual channel stimulator to be the main benefit of the system. The quantitative analysis presented here includes the results of 484 tests in 30 patients. For each test,(More)