Gregory S Wisdom

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The procyclic acidic repetitive protein (parp) genes of Trypanosoma brucei encode a small family of abundant surface proteins whose expression is restricted to the procyclic form of the parasite. They are found at two unlinked loci, parpA and parpB; transcription of both loci is developmentally regulated. The region of homology upstream of the A and B parp(More)
The procyclic acidic repetitive proteins (PARPs) of Trypanosoma brucei are developmentally regulated surface proteins encoded by a family of polymorphic genes. We have determined the complete nucleotide sequence of a novel member of the PARP gene family and investigated its expression. The amino acid sequence deduced from the parpA alpha gene showed a(More)
In a physiologic act as complex as swallowing, there are myriad causes of dysfunction that can disorder feeding and respiration with grave consequences. The appropriate diagnostic evaluation of dysphagia and aspiration along with a review of a range of surgical strategies to correct swallowing and aspiration disorders are presented in this article.
Laryngoceles and saccular cysts, while relatively rare, occur more often than the literature would suggest. In the past, most were diagnosed clinically in a symptomatic patient. Today, however, more patients suspected of head and neck cancer are being diagnosed with diagnostic radiographic procedures. Of 2,068 patients studied at M.D. Anderson Hospital and(More)
Inverting papilloma is a very uncommon neoplasm; however, its ability to destroy bone, recur after incomplete removal, and undergo malignant transformation makes it an important disease to recognize. Because early diagnosis and prompt treatment offer high rates of cure, it is important to be able to differentiate inverting papilloma from more benign nasal(More)
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