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The design, implementation, and capabilities of an extensible visualization system, UCSF Chimera, are discussed. Chimera is segmented into a core that provides basic services and visualization, and extensions that provide most higher level functionality. This architecture ensures that the extension mechanism satisfies the demands of outside developers who(More)
BACKGROUND Comparing related structures and viewing the structures in the context of sequence alignments are important tasks in protein structure-function research. While many programs exist for individual aspects of such work, there is a need for interactive visualization tools that: (a) provide a deep integration of sequence and structure, far beyond(More)
With the increase in the number of large, 3D, high-resolution nucleic acid structures, particularly of the 30S and 50S ribosomal subunits and the intact bacterial ribosome, advancements in the visualization of nucleic acid structural features are essential. Large molecular structures are complicated and detailed, and one goal of visualization software is to(More)
MidasPlus [6, 7] is an interactive molecular modeling system used to depict three dimensional macromolecular structures such as proteins and nucleic acids, to study how these structures spatially and chemically interact, and to study how small molecules such as drugs bind with these macromolecules, Effective interaction with macromolecular structures(More)
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