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  • Gregory J. Pazour, Bethany L. Dickert, +4 authors Douglas G. Cole
  • Medicine, Biology
  • The Journal of cell biology
  • 2000 (First Publication: 30 October 2000)
  • Intraflagellar transport (IFT) is a rapid movement of multi-subunit protein particles along flagellar microtubules and is required for assembly and maintenance of eukaryotic flagella. We cloned andContinue Reading
  • John A. Follit, Richard A. Tuft, Kevin Fogarty, Gregory J. Pazour
  • Biology, Medicine
  • Molecular biology of the cell
  • 2006 (First Publication: 14 June 2006)
  • Eukaryotic cilia are assembled via intraflagellar transport (IFT) in which large protein particles are motored along ciliary microtubules. The IFT particles are composed of at least 17 polypeptidesContinue Reading
  • Brian Palenik, Jane Grimwood, +35 authors Igor V. Grigoriev
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 2007 (First Publication: 1 May 2007)
  • The smallest known eukaryotes, at ≈1-μm diameter, are Ostreococcus tauri and related species of marine phytoplankton. The genome of Ostreococcus lucimarinus has been completed and compared with thatContinue Reading
  • Karl-Ferdinand Lechtreck, Eric Carl Johnson, +6 authors George B. Witman
  • Biology, Medicine
  • The Journal of cell biology
  • 2009 (First Publication: 28 December 2009)
  • In humans, seven evolutionarily conserved genes that cause the cilia-related disorder Bardet-Biedl syndrome (BBS) encode proteins that form a complex termed the BBSome. The function of the BBSome inContinue Reading