Gregory J . Peitz

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Imagine working in an environment where all patients undergoing mechanical ventilation are alert, calm, and delirium free. Envision practicing in an environment where nonvocal patients can effectively express their need for better pain control, repositioning, or emotional reassurance. Picture an intensive care unit where a nurse-led, interprofessional team(More)
OBJECTIVE The debilitating and persistent effects of ICU-acquired delirium and weakness warrant testing of prevention strategies. The purpose of this study was to evaluate the effectiveness and safety of implementing the Awakening and Breathing Coordination, Delirium monitoring/management, and Early exercise/mobility bundle into everyday practice. DESIGN(More)
OBJECTIVE To summarize the role of pharmacotherapy in the management of phenylketonuria (PKU) and to review the pharmacology, pharmacokinetics, pharmacodynamics, efficacy data, and safety profile of sapropterin for this indication. DATA SOURCES A literature search was conducted using MEDLINE (1966-May 2009), International Pharmaceutical Abstracts(More)
The management of pain, agitation, and delirium in critically ill patients can be complicated by multiple factors. Decisions to administer opioids, sedatives, and antipsychotic medications are frequently driven by a desire to facilitate patients' comfort and their tolerance of invasive procedures or other interventions within the ICU. Despite accumulating(More)
Non-steroidal anti-inflammatory drugs (NSAID) have been used to close the patent ductus arteriosus in neonates for over two decades. Ibuprofen lysine, a parenteral NSAID, is labeled for the treatment of patent ductus arteriosus in neonates who do not respond to conventional medical management. While sharing many of the same adverse effects as indomethacin,(More)
PURPOSE A case report describing high-dose argatroban for the treatment of heparin-induced thrombocytopenia (HIT) with thrombosis and associated considerations in interpreting laboratory monitoring data are presented. SUMMARY A 51-year-old woman with an extensive history of coronary artery disease arrived at the emergency department with complaints of(More)
Aliskiren gained FDA approval for the treatment of hypertension in 2007. It is the first approved pharmaceutical to manage hypertension by direct renin inhibition. With the introduction of novel drugs and mechanisms of action comes the challenge of monitoring for new unreported adverse events. The side effect profile for aliskiren has not yet been fully(More)
Infektionen sollten neben Fremdkörpern, Neoplasien, peptischen Ösophagitiden und psychogenen Störungen in die Differenzialdiagnose der Schluckstörung im Kindesalter einbezogen werden. Ein 8-jähriger Junge litt nach einem Türkeiaufenthalt an Fieber, Gewichtsverlust und schmerzhaften Schluckbeschwerden. Eine erhöhte BSG und eine Tuberkulinkonversion bei(More)
PURPOSE Nine recently published articles and one guideline with important implications for critical care pharmacy practice are summarized. SUMMARY The Critical Care Pharmacotherapy Literature Update (CCPLU) group includes more than 40 experienced critical care pharmacists across the United States. Group members monitor 29 peer-reviewed journals on an(More)