Gregory F Bonner

Learn More
liquids or solid food despite ongoing therapy for 12 days. After the patient’s informed consent was obtained, thalidomide was started at a dose of 200 mg. Three days after this initial dose, the dose was decreased to 100 mg/day because of excessive drowsiness. Institution of thalidomide therapy was almost immediately followed by partial resolution of the(More)
PURPOSE Recent reports have suggested that precolonoscopy bowel preparation is easier to tolerate if a small volume solution is used. Therefore, the aim of this study was to compare three oral solutions for colonoscopy to determine any changes in either patient compliance or cleansing ability. METHODS Four hundred fifty patients were prospectively(More)
OBJECTIVE:We sought to examine whether use of nonsteroidal antiinflammatory drugs (NSAIDs) in an outpatient inflammatory bowel disease (IBD) population is associated with an increased likelihood of active disease.METHODS:We reviewed records of initial outpatient visits of IBD patients to the principal author from June 1995 to December 1997, with regard to(More)
BACKGROUND AND AIMS We examined whether use of nonsteroidal anti-inflammatory drugs (NSAIDs) in outpatients with inflammatory bowel disease was associated with increased severity of disease activity. METHODS Outpatients with Crohn's disease (CD; n = 426) and with ulcerative colitis (UC; n = 203) were seen between November 1997 and April 2002. Patients(More)
Collagenous colitis and lymphocytic colitis cause chronic watery diarrhea. Multiple therapies have been found to improve symptoms but there have been few long-term follow-up studies. Our goal was to obtain long-term clinical follow-up on a cohort of patients with independently confirmed typical histopathologic changes. Pathology slides from 32 cases of(More)
Bile acid composition in fasting duodenal bile was assessed at entry and at 2 years in patients with primary biliary cirrhosis (PBC) enrolled in a randomized, double-blind, placebo-controlled trial of ursodeoxycholic acid (UDCA) (10-12 mg/kg/d) taken as a single bedtime dose. Specimens were analyzed by a high-pressure liquid chromatography method that had(More)
azathioprine and died. His colitis was in remission by that time, and death was not due to the hemophagocytic syndrome. Another two patients stopped azathioprine 8 months later because of persistently elevated liver enzymes and leucopenia, respectively. Twenty-one patients are well and disease is maintained in remission on azathioprine alone for a mean of 6(More)
Patients with an inflammatory bowel disease, such as ulcerative colitis or Crohn's disease, have recurrent symptoms with considerable morbidity. Patient involvement and education are necessary components of effective management. Mild disease requires only symptomatic relief and dietary manipulation. Mild to moderate disease can be managed with(More)