Gregory E. Glass

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Spatial epidemiology is the study of spatial variation in disease risk or incidence. Several ecological processes can result in strong spatial patterns of such risk or incidence: for example, pathogen dispersal might be highly localized, vectors or reservoirs for pathogens might be spatially restricted, or susceptible hosts might be clumped. Here, we(More)
BACKGROUND The mosquito-borne dengue viruses are a major public health problem throughout the tropical and subtropical regions of the world. Changes in temperature and precipitation have well-defined roles in the transmission cycle and may thus play a role in changing incidence levels. The El Niño Southern Oscillation (ENSO) is a multiyear climate driver of(More)
Norway rats (Rattus norvegicus) carry several zoonotic pathogens and because rats and humans live in close proximity in urban environments, there exists potential for transmission. To identify zoonotic agents carried by rats in Baltimore, Maryland, USA, we live-trapped 201 rats during 2005-2006 and screened them for a panel of viruses, bacteria, and(More)
The four dengue viruses, the agents of dengue fever and dengue hemorrhagic fever in humans, are transmitted predominantly by the mosquito Aedes aegypti. The abundance and the transmission potential of Ae. aegypti are influenced by temperature and precipitation. While there is strong biological evidence for these effects, empirical studies of the(More)
OBJECTIVES A geographic information system was used to identify and locate residential environmental risk factors for Lyme disease. METHODS Data were obtained for 53 environmental variables at the residences of Lyme disease case patients in Baltimore County from 1989 through 1990 and compared with data for randomly selected addresses. A risk model was(More)
The objective of this research is to explore what would happen if the Hong Kong influenza pandemic strain of 1968–1969 returned in 2000. We report the results of a series of simulations of an SEIR epidemic model coupled with air transportation data for 52 global cities. Preliminary results suggest that if the 1968–1969 pandemic strain returned, it would(More)
Anopheline mosquitoes were sampled inside houses, where residents slept under untreated bednets, by CDC light traps and human-biting catches to evaluate light traps as a means for determining human exposure to malaria vectors in Kilifi District, Kenya. Mosquitoes were sampled during 2 all-night collections by light traps and one all-night biting catch in a(More)
OBJECTIVE Gonorrhea has a focused geographic distribution characterized by high incidence rates in defined "core" areas and decreased incidence as the radial distance from the central core increases. Dense cor group transmission has long been hypothesized. METHODS We have previously mapped sexually transmitted disease (STD) rates in Baltimore census(More)
Movement of individuals promotes colonization of new areas, gene flow among local populations, and has implications for the spread of infectious agents and the control of pest species. Wild Norway rats (Rattus norvegicus) are common in highly urbanized areas but surprisingly little is known of their population structure. We sampled individuals from 11(More)
Malaria control interventions have been scaled-up in Zambia in conjunction with a malaria surveillance system. Although substantial progress has been achieved in reducing morbidity and mortality, national and local information demonstrated marked heterogeneity in the impact of malaria control across the country. This study reports the high burden of malaria(More)