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BACKGROUND Early switch to oral antibacterials is recommended for the treatment of hospitalized patients with community-acquired pneumonia (CAP). However, its efficacy and safety in patients with more severe forms of CAP have not been well established. OBJECTIVE To evaluate early switch to oral treatment in hospitalized patients with moderate to severe(More)
INTRODUCTION The early identification of the unstable carotid plaque together with the best medical treatment, are two missing parts of the stroke-prevention puzzle. This review summarizes the available evidence on the effects of statins on carotid plaque morphology. METHODS A systematic review of the PubMed, Scopus and Cochrane Library databases was(More)
INTRODUCTION Statins are currently used for hyperlipidaemia control and considered useful for protection from cardiovascular events. In addition, there is increasing evidence for the potential use of statins in preventing and treating infections. METHODS We performed a systematic review of the literature that compared the outcome between statin and(More)
We evaluated the clinical evidence regarding probiotic use for the prevention of respiratory tract infections (RTIs). Randomised controlled trials (RCTs) studying the effects of probiotics for the prevention of upper or lower RTIs were systematically identified. Fourteen RCTs (twelve involving healthy subjects and two involving patients with RTIs) were(More)
AIM To assess the utilisation of an interventional radiology day unit (RDU), the rates of on-time discharges, the financial performance of the unit, and finally, the patient satisfaction rates. MATERIALS AND METHODS Data regarding the unit utilisation, discharge times, and complications were retrospectively collected for the first 2 years of operation of(More)
BACKGROUND The potential need for re-evaluation of guidelines on surgical antimicrobial prophylaxis (AMP) in an era of advancing antimicrobial resistance is a matter of a considerable controversy. METHOD Review of the pertinent literature. RESULTS Over the last decade, the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) has increased(More)
Bacterial interference refers to the antagonism between bacterial species during the process of surface colonisation and acquisition of nutrients. The clinical evidence on the potential applications of microorganisms for the prevention and/or treatment of infections in the upper respiratory, urogenital and gastrointestinal tracts was reviewed through the(More)
BACKGROUND Pulsatile flow in deep, perforating veins and varicose veins (VVs) has been described previously to support a hypothesis of arteriovenous (AV) fistulae in the pathogenesis of VVs. Its presence has also been suggested as a cause of failure of VV treatments. However, AV communications have never been adequately visualized and direct pressure(More)
BACKGROUND China is one of the most rapidly developing countries with a huge population spreading on a chaotic area. For centuries Chinese medicine was based on tradition, religion and experience. However, the last two decades under the pressure of globalization Chinese medicine is turning gradually to evidence-based medicine, contributing in international(More)