Data Set Used
We report the draft genome of Streptomyces rimosus (ATCC 10970), a soil isolate that produces oxytetracycline, a commercially important and clinically useful antibiotic.
FK506 (Tacrolimus) is an important immunosuppressant, produced by industrial biosynthetic processes using various Streptomyces species. Considering the complex structure of FK506, it is reasonable to expect complex regulatory networks controlling its biosynthesis. Regulatory elements, present in gene clusters can have a profound influence on the final yield… (More)
Streptomyces rapamycinicus strain NRRL 5491 produces the important drug rapamycin. It has a large genome of 12.7 Mb, of which over 3 Mb consists of 48 secondary metabolite biosynthesis clusters.
A comparison between weak form meshless local Petrov-Galerkin method (MLPG) and strong form meshless diffuse approximate method (DAM) is performed for the diffusion equation in two dimensions. The shape functions are in both methods obtained by moving least squares (MLS) approximation with the polynomial weight function of the fourth order on the local… (More)
BACKGROUND Erythromycin is a medically important antibiotic, biosynthesized by the actinomycete Saccharopolyspora erythraea. Genes encoding erythromycin biosynthesis are organized in a gene cluster, spanning over 60 kbp of DNA. Most often, gene clusters encoding biosynthesis of secondary metabolites contain regulatory genes. In contrast, the erythromycin… (More)
The performance of the parallel implementation of the local meshless numerical method in solving system of coupled partial differential equations is explored. Presented numerical approach makes the computation convenient for parallel implementation using OpenMP based parallelization. The numerical experiments are performed on the de Vahl Davis natural… (More)
This paper introduces an effective H-adaptive upgrade to solution of the transport phenomena by the novel Local Radial Basis Function Collocation Method (LRBFCM). The transport variable is represented on overlapping 5-noded influence-domains through collocation by using multiquadrics Radial Basis Functions (RBF). The involved first and second derivatives of… (More)
In this paper, the summary of the doctoral thesis focused on the local meshless based solution procedure for solving a multiphase thermo-fluid flow is presented. Povzetek: V članku je predstavljen povzetek doktorskega dela, namenjenega reševanju večfaznega toplotno kapljevinskega toka preko lokalne brezmrežne numerične metode.