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We study the computational problem of identifying optimal sets of kidney exchanges in the UK. We show how to expand an integer programming-based formulation due to Roth et al. [2007] in order to model the criteria that constitute the UK definition of optimality. The software arising from this work has been used by the National Health Service Blood and(More)
(2008) The stable roommates problem with globally-ranked pairs. Abstract We introduce a restriction of the stable roommates problem in which roommate pairs are ranked globally. In contrast to the unrestricted problem, weakly stable matchings are guaranteed to exist, and additionally, can be found in polynomial time. However, it is still the case that(More)
A constraint programming approach to the hospitals / residents problem. Abstract. An instance I of the Hospitals / Residents problem (HR) involves a set of residents (graduating medical students) and a set of hospitals, where each hospital has a given capacity. The residents have preferences for the hospitals, as do hospitals for residents. A solution of I(More)
We consider variants of the classical stable marriage problem in which preference lists may contain ties, and may be of bounded length. Such restrictions arise naturally in practical applications, such as centralised matching schemes that assign graduating medical students to their first hospital posts. In such a setting, weak stability is the most common(More)
Cell surface expression of stage specific embryonic antigen 1 (SSEA-1), or Lex (III3 FucnLC4), was induced in differentiated human teratocarcinoma cells and in human diploid fibroblasts 3-6 d after infection with human cytomegalovirus (HCMV). In parallel, fucosylated lactoseries glycolipids bearing the SSEA-1/Lex epitope were readily detected in the(More)
In a model of peritoneal metastasis in immune-competent mice, we show that nuclear factor (NF)-κB inhibition in CT26 colon cancer cells prevents metastasis. NF-κB inhibition, by stable overexpression of IκB-α super-repressor, induced differential polarization of co-cultured macrophages to an M1-like anti-tumour phenotype in vitro. NF-κB-deficient cancer(More)
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