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Journals and Conferences
Rat fetuses exposed to a taste-odor stimulus and an aversive stimulus in utero showed an aversion to the taste/odor stimulus when tested 16 days postnatally. Fetuses which received various control treatments in utero did not show an aversion. These data show that rat fetuses at 20 days of gestation are capable of associative learning which can be… (More)
Pregnant albino rats were anesthetized with a combination of ketamine and xylazine. A minimal effective dosage of 90 mg/kg for ketamine and 10 mg/kg for xylazine provided satisfactory anesthesia in 92% of the subjects, without adverse effects on gestation or the fetuses.
Rat fetuses exposed to an odor stimulus and an aversive stimulus in utero showed an aversion to the odor when tested 16 days postnatally. Fetuses that also received 80 micrograms/kg Met-enkephalin showed a greater aversion to the odor stimulus than those subjects that did not receive the peptide. The difference between these groups was marginally… (More)
Hippocampal tissue from day 16 fetal rats was implanted into the damaged hippocampal formation of adults. Significant recovery of the lesion-induced deficit in spatial maze performance was observed, particularly in those animals which showed integration of the implanted fetal tissue with the host hippocampal formation. A two-stage procedure in which 2 weeks… (More)
The superficial lateral coccygeal veins of Macaca fascicularis were exposed surgically and cannulated with polyethylene tubing. The cannula was used for administering continuous infusions or obtaining multiple blood samples, and it was removed 12--18 hours after insertion.