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People who have remitted from depression are at increased risk for relapse if they rate their relatives as being critical of them on a simple self-report measure of Perceived Criticism (PC). To explore neural mechanisms associated with this we used functional magnetic resonance imaging (fMRI) to examine how people with different levels of PC responded to(More)
The term "functional connectivity" is used to denote correlations in activation among spatially-distinct brain regions, either in a resting state or when processing external stimuli. Functional connectivity has been extensively evaluated with several functional neuroimaging methods, particularly PET and fMRI. Yet these relationships have been quantified(More)
Modern pupillometry has expanded the study and utility of pupil responses in many new domains, including psychiatry, particularly for understanding aspects of cognitive and emotional information processing. Here, we review the applications of pupillometry in psychiatry for understanding patients' information processing styles, predicting treatment, and(More)
Neuroscientists have become increasingly interested in exploring dynamic relationships among brain regions. Such a relationship, when directed from one region toward another, is denoted by "effective connectivity." An fMRI experimental paradigm which is well-suited for examination of effective connectivity is the slow event-related design. This design(More)
There are many planning applications that require an agent to coordinate its activities with processes that change continuously over time. Several proposals have been made for combining a temporal logic of time with the differential and integral calculus to provide a hybrid calculus suitable for planning applications. We take one proposal and explore some(More)
Introduction The CLIM Prototyping environment (CPE) is an interactive graphical object manipulation environment developed at the Institute for the Learning 'sciences. The system functions as a user interface management system (UIMS) and can be used as a rnntime environment for arbitrary Common Lisp programs. In addition, interfaces may be created within CPE(More)
This special issue arose when, without a motivating act of editorial savvy, a number of excellent manuscripts, all on the topic of rumination, were submitted to Cognitive Therapy and Research. All articles in this special issue went through the regular peer review process. Having these articles together, which span themes from basic science to treatment(More)
The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters. Affective neutral reactivity to criticism in individuals high and low on perceived criticism. PLoS ONE 7(9): e44412. Abstract People who have remitted from depression are at increased risk for relapse if they rate their relatives as(More)