Greg Powell

Learn More
Internationally, the orphan crisis caused by the human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) pandemic remains a serious issue with long-term social consequences. At the end of 2001, an estimated 14 million children worldwide had lost their mother or both parents to AIDS or related causes. Sub-Saharan Africa is the most(More)
PURPOSE Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are medically serious skin reactions that are often drug induced. The mainstay of therapy and future prevention is to discontinue and avoid the use of the suspected inducing drug. However, many cases of SJS/TEN occur in patients who are taking multiple medications, and it is often(More)
PURPOSE The aim of this study was to develop an automated causality assessment algorithm to identify drug-induced liver injury. METHODS The Roussel Uclaf Causality Assessment Method (RUCAM) is an algorithm for determining the causal association between a drug and liver injury. In collaboration with hepatology experts, definitions were developed for the(More)
Large-scale tree improvement programs began in the 1950s. Tree improvement is now part of operational silviculture programs in many companies and countries around the world and tree breeding programs have produced very impressive results: (1) realized gains in plantations being established today of some 40–50 % in volume yield above unimproved material for(More)
Discovery of characteristic proteins expressed by a given cell type and how these proteins change during development or pathology, has only been feasible very recently. Powerful separation techniques coupled with the sensitivity and selectivity of mass spectrometry, are used to identify these proteins. Computer-based, bioinformatics techniques are used to(More)
  • 1