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To understand the structural basis of biology, it is necessary to understand the transformations of macromolecules during functional cycles. These changes can involve large-scale conformational transformations, changes in the state of ligation or association, changes in dynamics, or alterations in covalent bond structure. X-ray crystallography and NMR(More)
Twelve pregnant Brahman cows were randomly assigned to one of two treatment groups: 1) transported in a stock trailer for 24.2 km, unloaded at a second farm and penned for 1 hr, and then returned to the original farm (TRANS, n = 6); or 2) walked through the handling facilities (SHAM, n = 6). Treatments were repeated at 60, 80, 100, 120, and 140 d of(More)
In this article the efficacy of carbamazepine for seizure prophylaxis in severe head injuries is tested. In addition, conditions with high risk of seizures requiring prophylactic regimen, were defined. One hundred and thirty-nine patients above 15 years of age with severe head injuries were included in the study. They were randomly divided into two(More)
The appropriate dose and the ability of exogenous ACTH to mimic the physiological effects of a real stressor need to be determined. In Exp. 1, 25 pregnant Brahman heifers were injected i.v. with either 0 (saline), .125, .25, .5, or 1 i.u. of ACTH/kg BW. Plasma cortisol was determined in blood samples collected during a 5-h period, and an integrated cortisol(More)
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