Grayce M. Booth

Learn More
Ethylene glycol dimethyl ether (EGdiME), diethylene glycol dimethyl ether (diEGdiME), triethylene glycol dimethyl ether (triEGdiME), diethylene glycol diethyl ether (diEGdiEE), ethylenethiourea (ETU), sodium selenite (SS), dimethyl phthalate (DMP), naphthalene (NAP), or p-nitrophenol (PNP) were administered by gavage for eight consecutive days to female(More)
The number of chemicals in commerce which have not been evaluated for potential developmental toxicity is large. Because of the time and expense required by conventional developmental toxicity tests, an abbreviated assay is needed that will preliminarily evaluate otherwise untested chemicals to help prioritize them for conventional testing. A proposed(More)
Recent studies demonstrate that endothelin-1 (ET-1) constricts human pulmonary arteries (PA). In this study, we examined possible mechanisms by which ET-1 might constrict human PA. In smooth muscle cells freshly isolated from these arteries, whole cell patch-clamp techniques were used to examine voltage-gated K(+) (K(V)) currents. K(V) currents were(More)
Cholinesterase from frozen sections of honey bee (Apis mellifera, L.) brain hydrolyzes phenylthioacetate and acetylthiocholine to give virtually identical patterns of enzyme distribution with and without the use of paraoxon. In addition, phenylthioacetate is an economical substrate for in vitro and in vivo studies of cholinesterase. Phenylthioacetate offers(More)
Distributed information systems represent an increasingly important trend to computer users. Distributed processing is a technique for implementing a single logical set of processing functions across a number of physical devices, so that each performs some part of the total processing required. Distributed processing is often accompanied by the formation of(More)
Fifteen glycol ethers were investigated for their potential to cause adverse reproductive toxic effects using an in vivo mouse screening bioassay. Pregnant mice were orally dosed once per day on days 7 through 14 of gestation at concentrations causing 0 to 41% maternal mortality. Reproductive endpoints included pup survival in utero (percent of live(More)
Di-2-ethylhexyl phthalate (DEHP), often referred to as dioctyl phthalate or DOP, is the most widely used plasticizer for vinyl plastics, and approximately 350 million pounds were produced in the United States during 1970. Altogether the production of phthalate ester plasticizers was 855 million pounds (1). The cumulative production of DEHP and related(More)
Remote information processing is the computer community's wave of the future. For both computer users and for computer vendors it represents an enormous opportunity. To the user, it is a powerful tool with great potential to increase his business efficiency and profit. To the vendor, it opens a broad new market. Properly used, it can benefit both.
Effects of gossypol treatment were studied in pregnant mice and chick embryos. Pregnant Balb C mice were treated orally with 60 or 120 mg/kg of gossypol acetic acid on days 6-13 of pregnancy and killed on day 18. The uteri were removed, the number of resorptions and late fetal deaths were recorded, and the fetuses were weighed and assessed for(More)