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The development of tools in computational pathology to assist physicians and biomedical scientists in the diagnosis of disease requires access to high-quality annotated images for algorithm learning and evaluation. Generating high-quality expert-derived annotations is time-consuming and expensive. We explore the use of crowdsourcing for rapidly obtaining(More)
Patients with adult-onset metachromatic leukodystrophy (MLD) often present with personality changes or deterioration of cognitive functions. Although rare, this form of MLD should be included in the differential diagnosis of psychotic and dementing disorders. The following case report describes a 38-year-old man with adult-onset MLD, who carried the(More)
TITLE: Sex and microhabitat influence the allocation of mycosporine-like amino acids to tissues in the purple sea urchin, Strongylocentrotus purpuratus Field surveys of Strongylocentrotus purpuratus demonstrated that concentrations of natural sunscreens, mycosporine-like amino acids (MAAs), were higher in females than males for both gonadal and epidermal(More)
The management of sex offenders is a complex and frustrating biopsychosocial problem. Treatment programs are experimental and few in number. The Department of Psychiatry at University Hospitals of Cleveland has developed a treatment program for male sex offenders that uses weekly injections of an antiandrogen medication, medroxyprogesterone acetate (MPA),(More)
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