Grant J Sormunen

  • Citations Per Year
Learn More
The control of regiochemistry is a considerable challenge in the development of a wide array of catalytic processes. Simple π-components such as alkenes, alkynes, 1,3-dienes, and allenes are among the many classes of substrates that present complexities in regioselective catalysis. Considering an internal alkyne as a representative example, when steric and(More)
Allylic alcohols are integral subunits of a variety of biologically interesting natural products as well as key building blocks for a number of important synthetic transformations. Among the numerous strategies for the preparation of allylic alcohols, the reductive coupling of aldehydes and alkynes in either an interor intramolecular sense arguably provides(More)
A strategy for catalyst-controlled regioselectivity in aldehyde-alkyne reductive couplings has been developed. This strategy is the first where either regiochemical outcome may be selected for a broad range of couplings, without relying on substrate biases or directing effects. The complementary use of small cyclopropenylidene carbene ligands or highly(More)
An exceptionally hindered class of enantiopure NHC ligands has been developed. While racemic forms had previously been utilized, a scalable and practical route to the enantiopure form of this ligand class is described utilizing a Buchwald-Hartwig N,N-diarylation in a highly sterically demanding environment. Using this newly accessible ligand class,(More)
  • 1