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The cell line PC12, derived from an adrenal chromaffin cell tumor, expresses both ganglionic (C6) acetylcholine receptors (nAChR) and an alpha-bungarotoxin (BGT) binding protein of unknown function. We measured nicotinic Na+ fluxes of 180-260 nmol/mg protein X min and 0.35-0.8 pmol [125I]BGT binding sites/mg protein; 45-65% of the [125I]BGT binding was to(More)
  • Graham Kemp
  • American journal of physiology. Cell physiology
  • 2008
TO THE EDITOR: Glancy et al. (4) measure the rate of oxygen consumption (Jo) by mitochondria incubated with an ATPconsuming system in the presence of creatine kinase (CK), and they show that this in vitro model of aerobically exercising skeletal muscle conforms to Meyer’s electrical analog of muscle oxidative phosphorylation in vivo (23). I want to suggest(More)
We used in situ autoradiographic ligand binding methods to determine the occurrence and distribution of dopamine D(1) and D(2) receptor sub-types in the anole lizard, Anolis carolinensis. Both were present and exhibited pharmacological specificity characteristics similar to those described for mammals. However, unlike in mammals where in the neostriatum(More)