Graham Derrick

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BACKGROUND Aortic arch geometry is linked to abnormal blood pressure (BP) response to maximum exercise. This study aims to quantitatively assess whether aortic arch geometry plays a role in blood pressure (BP) response to exercise. METHODS 60 age- and BSA-matched subjects--20 post-aortic coarctation (CoA) repair, 20 transposition of great arteries post(More)
OBJECTIVE To compare patient-reported, health-related quality of life (QoL) for children with serious congenital heart defects (CHDs) and unaffected classmates and to investigate the demographic and clinical factors influencing QoL. DESIGN Retrospective cohort study. SETTING UK National Health Service. PATIENTS UK-wide cohort of children with serious(More)
OBJECTIVE To define the range and variability of ambulatory blood pressure in normal schoolchildren. DESIGN Prospective study. METHODS Resting blood pressure of 1121 schoolchildren from Newcastle upon Tyne was recorded. An ambulatory blood pressure device, which uses both auscultatory (Korotkoff) and oscillometric methods of blood pressure measurement,(More)
OBJECTIVES To assess the communication potential of three-dimensional (3D) patient-specific models of congenital heart defects and their acceptability in clinical practice for cardiology consultations. DESIGN This was a questionnaire-based study in which participants were randomised into two groups: the 'model group' received a 3D model of the cardiac(More)
BACKGROUND This study assesses the relationship between septal curvature and mean pulmonary artery pressure and indexed pulmonary vascular resistance in children with pulmonary hypertension. We hypothesized that septal curvature could be used to estimate right ventricular afterload and track acute changes in pulmonary hemodynamics. METHODS AND RESULTS(More)
Abnormalities in aortic arch geometry do not lead to reduced exercise performance: a comparison study between patients with transposition of the great arteries repaired by arterial switch operation and normal controls
Use of CMR-based wave intensity analysis to demonstrate abnormalities in the aorta, the ventricle and ventriculo-arterial coupling: Comparison between patients with complete transposition of the great arteries (TGA), following palliation with atrial switch and arterial switch operations, and normals
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