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The interruption of malaria transmission worldwide is one of the greatest challenges for international health and development communities. The current expert view suggests that, by aggressively scaling up control with currently available tools and strategies, much greater gains could be achieved against malaria, including elimination from a number of(More)
– Tumor/abnormality segmentation from magnetic resonance imagery (MRI) can play a significant role in cancer research and clinical practice. Although accurate tumor segmentation by radiologists is ideal, it is extremely tedious. Experience shows that for MRI database indexing purposes approximate segmentations can be adequate. In this paper, we propose a(More)
  • Philippe Boeuf, Elizabeth H. Aitken, Upeksha Chandrasiri, Caroline Lin Lin Chua, Bernie McInerney, Leon McQuade +5 others
  • 2013
Placental malaria (PM) can lead to poor neonatal outcomes, including low birthweight due to fetal growth restriction (FGR), especially when associated with local inflammation (intervillositis or IV). The pathogenesis of PM-associated FGR is largely unknown, but in idiopathic FGR, impaired transplacental amino acid transport, especially through the system A(More)
Over the past decade, significant gains have been made in the implementation of malaria prevention measures in pregnancy in sub-Saharan Africa, including the distribution of insecticide-treated nets (ITNs). These have been shown to cause a reduction in the incidence of malaria and its consequences such as maternal anaemia, stillbirths and intrauterine(More)
  • Gregory M. Vercellotti, Fatima B. Khan, Julia Nguyen, Chunsheng Chen, Carol M. Bruzzone, Heather Bechtel +5 others
  • 2014
Hemolysis, oxidative stress, inflammation, vaso-occlusion, and organ infarction are hallmarks of sickle cell disease (SCD). We have previously shown that increases in heme oxygenase-1 (HO-1) activity detoxify heme and inhibit vaso-occlusion in transgenic mouse models of SCD. HO-1 releases Fe(2+) from heme, and the ferritin heavy chain (FHC) ferroxidase(More)
  • Benjamin R. Bavinton, Martin Holt, Andrew E. Grulich, Graham Brown, Iryna B. Zablotska, Garrett P. Prestage +1 other
  • 2016
HIV 'treatment as prevention' (TasP) is highly effective in reducing HIV transmission in serodiscordant couples. There has been little examination of gay and bisexual men's attitudes towards TasP, particularly regarding men's willingness to act on beliefs about TasP. We conducted an online cross-sectional survey of Australian men in late 2012 to investigate(More)
INTRODUCTION Treatment as prevention has mobilized new opportunities in preventing HIV transmission and has led to bold new UNAIDS targets in testing, treatment coverage and transmission reduction. These will require not only an increase in investment but also a deeper understanding of the dynamics of combining behavioural, biomedical and structural HIV(More)
Territorial marking allows people to communicate that a territory has been claimed. Across 2 studies, we examine the impact of territorial marking of one's ideas on others' invited creativity when asked to provide feedback. Integrating research on territoriality and self-construal, we examine the effect of control-oriented marking on invited creativity(More)