Graeme Bredo

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527 patients with cranial traumas aged between 15 days and 13 years 10 months old were examined. All the subjects were treated at the Paediatric Division of Biella Hospital in 1972-1982, and were given cranial radiography. The most frequent types of trauma for the different age groups were noted, together with any correspondence between clinical signs and(More)
Human CRTh2(+) Th2 cells express IL-25 receptor (IL-25R) and IL-25 has been shown to potentiate production of Th2 cytokines. However, regulation of IL-25R and whether it participates in Th2 differentiation of human cells have not been examined. We sought to characterize IL-25R expression on CD4(+) T cells and determine whether IL-25 plays a role in Th2(More)
PGD₂ has long been implicated in allergic diseases. Recent cloning of a second PGD₂ receptor, DP2 (also known as CRTh2), led to a greater understanding of the physiological and pathophysiological implications of PGD₂. PGD₂ signaling through DP1 and DP2 mediates different and often opposite effects in many cell types of the immune system. Although mast cells(More)
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