Grace O'Malley

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OBJECTIVE To determine if beneficial effects of a weight-management program could be sustained for up to 24 months in a randomized trial in an ethnically diverse obese population. PATIENTS AND METHODS There were 209 obese children (BMI > 95th percentile), ages 8 to 16 of mixed ethnic backgrounds randomly assigned to the intensive lifestyle intervention or(More)
PURPOSE : Evidence suggests a negative effect of obesity on musculoskeletal health in children. A pilot study was undertaken to investigate the presence of musculoskeletal impairments in children with obesity and to explore the relationships among body mass index, physical activity, and musculoskeletal measures. METHODS : Lower limb musculoskeletal health(More)
OBJECTIVE While indexes have been proposed to estimate total and abdominal adiposity in adults, the assessment of adiposity among obese adolescents remains difficult in clinical setting. The aim of this study was to evaluate the clinical applicability of total and visceral and fat mass indexes in obese adolescents. METHODS One hundred and thirty, 12-16(More)
OBJECTIVE To characterize adults with comorbid attention-deficit/hyperactivity-disorder (ADHD) and borderline personality disorder (BPD) with regard to ADHD symptoms, psychopathology, cognitive functioning and psychosocial factors. METHOD A between-group design compared a group of individuals diagnosed with ADHD (n=40) with a group diagnosed with BPD and(More)
INTRODUCTION Early assessment of a therapeutic response is a central goal in antidepressant treatment. The present study examined the potential for therapeutic drug monitoring and symptom rating to predict venlafaxine treatment efficacy (measured by overall patient response and remission). METHODS 88 patients were uptitrated homogenously to 225 mg/day(More)
BACKGROUND Recently, the deleterious metabolic effects of visceral fat [visceral adipose tissue (VAT)] deposition were challenged, and liver fat emerged as having a key independent role in the modulation of cardiometabolic risk factors. OBJECTIVE We explored the relation between liver fat content and VAT in 3 ethnic groups and evaluated whether the ethnic(More)
The increasing prevalence of paediatric obesity and related metabolic complications has been mainly associated with lower aerobic fitness while less is known regarding potential musculoskeletal impairments. The purpose of the present systematic review was to report the evidence regarding muscular fitness in children and adolescents with obesity. A(More)
INTRODUCTION Current diagnostic classifications regard psychotic symptoms during depressive episodes as indicators of depression severity. However, growing evidence suggests that depression with psychotic symptoms (MDP) may represent a distinct subtype of depression. In the course of the search for discriminating factors we tested the hypothesis that the(More)
a The Children’s Obesity Clinic, Department of Paediatrics, Copenhagen University Hospital Holbæk, Holbæk , Denmark, b Unit of Pediatrics, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute, Stockholm , Sweden, c Department of Community Medicine and Primary Care, Geneva University Hospitals, Geneva , Switzerland, d(More)
BACKGROUND Obesity is a global epidemic. Behavioral change approaches towards improving nutrition, increasing physical activity level, improving sleep, and reducing sitting time are recommended as best practices in adolescent obesity management. However, access to evidence-based treatment is limited and portable technologies such as mobile apps may provide(More)