Learn More
The auditory system operates over a vast range of sound pressure levels (100-120 dB) with nearly constant discrimination ability across most of the range, well exceeding the dynamic range of most auditory neurons (20-40 dB). Dean et al. (2005) have reported that the dynamic range of midbrain auditory neurons adapts to the distribution of sound levels in a(More)
Auditory adaptation to sound-level statistics occurs as early as in the auditory nerve (AN), the first stage of neural auditory processing. In addition to firing rate adaptation characterized by a rate decrement dependent on previous spike activity, AN fibers show dynamic range adaptation, which is characterized by a shift of the rate-level function or(More)
The Weber–Fechner law states that perceived intensity is proportional to physical stimuli on a logarithmic scale. In this work, we formulate a Bayesian framework for the scaling of perception and find logarithmic and related scalings are optimal under expected relative error fidelity. Therefore, the Weber–Fechner law arises as being information(More)
Determining the rupture pressure threshold of ultrasound contrast agent microbubbles has significant applications for contrast imaging, development of therapeutic agents, and evaluation of potential bioeffects. Using a passive cavitation detector, this work evaluates rupture based on acoustic emissions from single, encapsulated, gas-filled microbubbles.(More)
The spatio-temporal pattern of auditory nerve (AN) activity, representing the relative timing of spikes across the tonotopic axis, contains cues to perceptual features of sounds such as pitch, loudness, timbre, and spatial location. These spatio-temporal cues may be extracted by neurons in the cochlear nucleus (CN) that are sensitive to relative timing of(More)
The reproductive ability of 24 men exposed to lead was observed and the same number of no-exposed men were taken as controls. The influential factors, such as age, smoking and drinking were controlled. The finding shows higher prevalence of congenital epilepsy and heart disease in the filial generation of workers exposed to lead and high rate of(More)
The long-term goal of this project is to understand the neural mechanisms that mediate the ability of normal-hearing people to understand speech and localize sounds in complex acoustic environments comprising reverberation and competing sound sources. In the past year, we focused on two research projects: (1) Physiological and psychophysical studies of(More)
The long-term goal of our research is to understand the neural mechanisms that mediate the ability of normal-hearing people to understand speech and localize sounds in everyday acoustic environments comprising reverberation and competing sound sources. In the past year, we continued work on three areas: (1) Physiological studies of sound localization in(More)
Auditory adaptation to sound level statistics occurs as early as in the auditory nerve (AN), the 11 first stage of neural auditory processing. In addition to firing rate adaptation characterized by a 12 rate decrement dependent on previous spike activity, AN fibers show dynamic range adaptation, 13 which is characterized by a shift of the rate-level(More)