Learn More
Evidence from model organisms and clinical trials reveals that the random insertion of retrovirus-based vectors in the genome of long-term repopulating hematopoietic cells may increase self-renewal or initiate malignant transformation. Clonal dominance of nonmalignant cells is a particularly interesting phenotype as it may be caused by the dysregulation of(More)
Inner centromere protein (INCENP) is a part of a protein complex known as the chromosomal passenger complex (CPC) that is essential for correcting non-bipolar chromosome attachments and for cytokinesis. We here demonstrate that a protein arginine methyltransferase PRMT1, which are overexpressed in various types of cancer including lung and bladder cancer,(More)
Updated information and services can be found at: (166 articles) Stem Cells in Hematology (795 articles) Oncogenes and Tumor Suppressors (3094 articles) Hematopoiesis and Stem Cells Articles on similar topics can be found in the following Blood collections
  • 1