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A model system for [NiFe] hydrogenase maturation studies: Purification of an active site‐containing hydrogenase large subunit without small subunit
The large subunit HoxC of the H2‐sensing [NiFe] hydrogenase from Ralstonia eutropha was purified without its small subunit. Two forms of HoxC were identified. Both forms contained iron but onlyExpand
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A Universal Scaffold for Synthesis of the Fe(CN)2(CO) Moiety of [NiFe] Hydrogenase*
Background: The active site iron of [NiFe] hydrogenases is equipped with a carbonyl ligand (CO) and two cyanides (CN−). Results: A complex of the hydrogenase accessory proteins HypC and HypD containsExpand
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Synthesis, characterization, and biodistribution of multiple 89Zr-labeled pore-expanded mesoporous silica nanoparticles for PET.
Functional nanoparticles are highly interesting imaging agents for positron emission tomography (PET) due to the possibility of multiple incorporation of positron emitting radionuclides thusExpand
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Inside BOSS: South Africa's secret police
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The role of the active site-coordinating cysteine residues in the maturation of the H2-sensing [NiFe] hydrogenase from Ralstonia eutropha H16
The H2-splitting active site of [NiFe] hydrogenases is tightly bound to the protein matrix via four conserved cysteine residues. In this study, the nickel-binding cysteine residues of HoxC, the largeExpand
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Crystallization and preliminary X-ray crystallographic analysis of the [NiFe]-hydrogenase maturation factor HypF1 from Ralstonia eutropha H16.
The hydrogenase maturation factor HypF1 is a truncated but functional version of the HypF protein. HypF is known to be involved in the supply of the CN(-) ligands of the active site ofExpand
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Canada and the French-Canadian Question
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