Gordon James McArthur

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Twelve previously untreated patients with Ph1-positive chronic myeloid leukaemia received combination chemotherapy soon after diagnosis. There was karyotypic conversion in five: in four, the percentage of Ph1-positive cells fell to 10 or less. In two other patients, who had mosaic karyotypes at presentation, the percentage fell to 5% and zero.
An 88-year-old man, receiving prednisolone for sarcoidosis, presented with a discrete keratotic lesion on the dorsum of his right hand following the placement of an intravenous cannula a month prior to its appearance. Medicopsis romeroi was isolated from the tissue and identified by sequencing the internal transcribed spacer region ITS-1 and the D1-2(More)
Melanocytic lesions of uncertain malignant potential (MUMP) is a term which is useful in identifying melanocytic tumours where the distinction between benign and malignant is a histological problem. Sentinel node biopsy is recognised to provide unmatched prognostic information in melanoma patients, but has recently been advocated for diagnostic purposes in(More)
Many burns surgeons avoid excision and direct closure of acute burns owing to concerns over wound dehiscence, scarring and infection. There is no evidence in the literature to support this practice. We present outcomes of a prospective series of 100 patients who underwent excision and direct closure of 138 burns over a 2-year period, along with results from(More)
resulting in large defects that make reconstruction difficult. Satisfactory reconstruction of these complex jaw defects, especially in a single-stage procedure using vascularized FFF, is therefore a surgical challenge in most developing countries. Although several reports have examined immediate mandibular reconstruction after mandibulectomy secondary to(More)
In a recent follow-up review of 45 patients (49 hands) treated by simple trapeziectomy for osteoarthritis of the trapeziometacarpal joint carried out 26 months (range 15 to 26) after surgery, 20 of the patients (21 hands) reported that the hand was clumsier than before the operation, when specifically asked about this symptom. They had trouble doing(More)