Gordon Jacobson

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UNLABELLED The study was designed to characterize L-[methyl-11 C]methionine accumulation in abnormal parathyroid tissues of hyperparathyroidism (HPT). METHODS Thirty-four patients with primary (n = 32) or secondary HPT were investigated with PET before primary or reoperative (n = 25) parathyroid surgery. Parathyroid 11C-methionine accumulation was(More)
BACKGROUND Radiologic diagnosis of pancreatic tumors exhibits limited precision. The aim of this study was to investigate the outcome and complications of pancreatic core biopsy in patients with suspected pancreatic neoplasms. METHODS One hundred patients underwent ultrasonography-guided core biopsy of 1.2 mm external diameter. Medical charts were(More)
BACKGROUND Congestive heart failure is the leading cause of hospital admissions for adults in the United States. To our knowledge, there are limited data comparing the clinical presentation, hospital length of stay, and readmission in patients with preserved and decreased left ventricular (LV) systolic function. HYPOTHESIS The goal of the study was to(More)
an early undiagnosed pancreatic tumour (Kessler, 1970; Wynder et al., 1973; Ragozzino et al., 1982; Manousos et al., 1981). An association between gall stone disease and pancreatic cancer has also been suggested, but the findings have been somewhat contradictory (Wynder et al., 1973; Manousos et al., 1981; Haines et al., 1982). In a recent casecontrol study(More)
Positron-emitting radionuclides have short half-lives and high radiation energies compared with radioisotopes generally used in biomedical research. We examined the possibility of applying positron emitter-labeled compounds to functional imaging in brain slices kept viable in an oxygenated buffer solution. Brain slices (300 microns thick) containing the(More)
PURPOSE To design and validate a survey instrument that measures vision-related functional status, which is appropriate for self-administration in a clinical practice and mail survey setting. DESIGN Observational, validation study in sequential patients. METHODS A prototype visual function instrument (the Cataract TyPE Spec) was developed based on focus(More)
Twenty-four patients with probably resectable carcinoma of the head of the pancreas were examined by means of CT, ERCP and US and supplemented with angiography to assess the resectability. Resection was possible in half of the patients. As the series consisted only of potentially resectable cases, those with obvious liver metastases at CT or US were not(More)
Biliary obstruction was treated with endoprosthetic drainage in 30 patients with pancreatic, 10 with gallbladder and 27 with biliary duct cancer, and 13 of the patients received more than one endoprosthesis. The median survival time in the respective cancer groups was 12, 10 and 9 weeks, including 6, 3 and 4 weeks spent in the patients' own homes. The(More)
Supercritical fluid extraction (SFE) of 11C-labeled tracer compounds and their metabolites from biological tissue was performed using supercritical ammonia in an attempt to develop a rapid extraction procedure that allowed subsequent analysis of the labeled metabolites. Metabolites were extracted from kidneys and brain in rats given in vivo injections of(More)