Gordana Pavlovic

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A formulation for maximum-likelihood (ML) blur identification based on parametric modeling of the blur in the continuous spatial coordinates is proposed. Unlike previous ML blur identification methods based on discrete spatial domain blur models, this formulation makes it possible to find the ML estimate of the extent, as well as other parameters, of(More)
Sequencing projects have identified large numbers of rare stop gain and frameshift variants in the human genome. Because most of these are observed in the heterozygous state, they test the genome's tolerance to dominant loss of function. We analyzed the distribution of truncating variants in 16818 protein coding autosomal genes from the exomes of 11546(More)
(2014) Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome. Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans. (2013) Myotonic dystrophy CTG expansion affects synaptic vesicle proteins, neurotransmission and(More)
AIMS AND OBJECTIVES We assessed the clinical impact of goal-directed coagulation management based on rotational thromboelastometry (ROTEM) in patients undergoing emergent cardiovascular surgical procedures. MATERIALS AND METHODS Over a 2-year period, data from 71 patients were collected prospectively and blood samples were obtained for coagulation(More)
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