Gopinath Venugopal

Learn More
The pattern of nerve differentiation along the body column of Hydra was investigated. Nerve precursors in late S phase were labeled with ['Hlthymidine and their distribution compared with that of newly differentiated nerves. The two distributions were found to be the same. Based on independent evidence that nerve commitment occurs in mid-to late S phase (G.(More)
The kinetics of nerve differentiation were investigated during head regeneration in Hydra. In particular the cell cycle parameters of stem cells undergoing nerve commitment were determined. Head regeneration induces extensive nerve commitment localized at the regenerating tip (G. Venugopal appearance of committed nerve precursors is followed 12 hr later by(More)
The kinetics of nerve commitment during head regeneration in Hydra were investigated using a newly developed assay for committed cells. Committed nerve precursors were assayed by their ability to continue nerve differentiation following explanation of small pieces of tissue. Committed nerve precursors appear at the site of regeneration within 6 hr after(More)
BACKGROUND Monocytes and macrophages contribute to the dysfunction of immune responses in human filariasis. During patent infection monocytes encounter microfilariae in the blood, an event that occurs in asymptomatically infected filariasis patients that are immunologically hyporeactive. AIM To determine whether blood microfilariae directly act on blood(More)
Optimal in vitro testing conditions for caprine alternative complement pathway assay were determined. Effects of the following variables were tested: heterologous erythrocytes; pH, ionic strength and Mg2+ ion concentration of the complement diluent; incubation time and temperature. Rabbit erythrocytes were the optimal target cells. The optimal buffer(More)
  • 1