Gopi Dandamudi

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BACKGROUND Fragmented QRS (duration <120 ms) on a 12-lead ECG represents myocardial scar in patients with coronary artery disease. However, the significance of fragmented QRS has not been defined in the presence of a wide QRS (wQRS; duration >or=120 ms). We postulate that fragmented wQRS (f-wQRS) due to bundle branch block, premature ventricular complexes,(More)
BACKGROUND Fragmented QRS (fQRS) on a 12-lead electrocardiogram (ECG) is associated with myocardial scar in patients with coronary artery disease (CAD). OBJECTIVE We postulated that fQRS is a predictor of cardiac events and mortality in patients who have known CAD or who are being evaluated for CAD. METHODS The cardiac events (myocardial infarction,(More)
BACKGROUND Complete electrical isolation of pulmonary veins (PVs) remains the cornerstone of ablation therapy for atrial fibrillation. Entrance block without exit block has been reported to occur in 40% of the patients. Far-field capture (FFC) can occur during pacing from the superior PVs to assess exit block, and this may appear as persistent conduction(More)
Chronic right ventricular (RV) pacing has been shown over the years to exert detrimental physiological changes including increased risk for heart failure and atrial fibrillation. His bundle pacing offers the promise of physiological activation of the ventricular tissue, with the potential for reducing the detrimental effects of RV pacing. We describe His(More)
BACKGROUND Right ventricular pacing (RVP) has been associated with heart failure and increased mortality. His-bundle pacing (HBP) is more physiological but requires a mapping catheter or a backup right ventricular lead and is technically challenging. OBJECTIVE We sought to assess the feasibility, safety, and clinical outcomes of permanent HBP in an(More)
INTRODUCTION His-bundle (HB) pacing (P) is a physiological alternative to right ventricular pacing (RVP), but is technically challenging and limited by higher pacing thresholds. Myocardial injury current (IC) recorded during right ventricular lead placement implies good tissue contact and is associated with low-pacing thresholds. IC at the HB has not been(More)
BACKGROUND The outcomes of patients with ventricular assist devices (VADs) who undergo catheter ablation for ventricular tachycardia (VT) have not been reported. OBJECTIVE The purpose of this study was to assess the feasibility, safety, and efficacy of endocardial VT ablation in patients with VADs. METHODS We retrospectively reviewed three cases at our(More)
BACKGROUND Various diagnostic maneuvers have been proposed to help differentiate orthodromic reciprocating tachycardia (ORT) from atrioventricular nodal reentrant tachycardia (AVNRT) prior to ablation. However, not all criteria are applicable in every situation as each has limitations. OBJECTIVE The purpose of this study was to determine whether the(More)
BACKGROUND Tachycardia-induced cardiomyopathy (TIC) seems to be a form of reversible cardiomyopathy. With recurrence, TIC can be more severe and may increase the risk for sudden cardiac death. OBJECTIVE We postulate that negative remodeling persists even though ejection fraction (EF) normalizes after appropriate treatment in these patients. METHODS We(More)