Gopalakrishnan Lakshmi

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The levels of the neurotransmitter amino acids glutamate, aspartate, and GABA were determined in different brain regions during ischemia and post-ischemic recirculation periods using the unilateral carotid artery occlusion model of stroke in gerbils. The levels of glutamate, aspartate and GABA in ischemic hemisphere were increased significantly by 10 min of(More)
The purpose of this study was to evaluate the feasibility and safety of renal artery angioplasty and stenting utilizing a distal protection device to reduce the risk of intraprocedural artery embolism and avoid deterioration of the renal function. Fifty-six hypertensive patients (32 men; mean age, 66 +/- 11.8 years; range, 22-87) with atherosclerotic renal(More)
Percutaneous transluminal angioplasty with or without stenting of steno-occlusions in the supra-aortic arch vessels in aortoarteritis is associated with suboptimal results and higher restenosis rates, particularly in those with diffuse disease. We report two cases of stand-alone cutting balloon angioplasty for patients who presented with critical stenosis(More)
Renal angioplasty and stenting have become the first treatments to be proposed to patients presenting with renal artery stenosis. The immediate technical success rate is high, with a low complication rate and good long-term patency. In most reports, renal stenting has been proven to improve blood pressure. However, despite good immediate- and long-term(More)
OBJECTIVE To assess the time trends in the prevalence of diabetes at our Centre from 1994-2004 (N: 19,072 individuals) on the following parameters: age group, sex, rural or urban area and individuals with freshly diagnosed diabetes versus known diabetes. STUDY DESIGN AND SETTING Analysis of data from electronic medical records at a referral Endocrine and(More)
Sixty rural children who were seronegative for HBV markers received three doses of 10 microgram of a new Hepatitis-B vaccine, Revac-B (1 ml of vaccine contains 20 microgram recombinant surface antigen) that was formulated from hepatitis-B surface antigen expressed in a recombinant strain of Saccharomyces cerevisiae. Vaccines were administered on a 0, 30 and(More)
Adrenomedullin-2 (ADM2), a novel calcitonin/calcitonin-gene related peptide family with an exon-intron structure similar to that of ADM. The aim of the present study is to evaluate the role of Adrenomedullin-2 (ADM2) on fetoplacental development in female pregnant albino rats and to evaluate the effect of adrenomedullin2 antagonist (ADM2 17-47) on fetal and(More)
A voltage source inverter with variable frequency and variable voltage is applied for three-phase interior permanent magnet synchronous motor (IPMSM) drive for variable speed application. To obtain the required output voltage in the line side of the inverter a suitable pulse width modulation technique is used. The most prominent PWM techniques are(More)
In this paper a simulation analysis of DTC-CBSVPWM of SPMSM drive using five-level diode clamped inverter is analyzed. It has simple structure and provides dynamic behavior comparable with classical DTC. Direct Torque Control (DTC) is an accurate controller for permanent magnet synchronous motor (PMSM) due to its robust and fast torque response in(More)
BACKGROUND Neurologic events associated with distal embolization of debris during percutaneous carotid artery stenting complicate the procedure. Filter devices for cerebral protection potentially reduce the risk of embolization and other neurologic events. We studied the feasibility, safety, and efficacy of carotid artery stenting with a filter device. (More)