Gopal Bhaskaran

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Juvenile hormone III plays a major role in regulating feeding and reproduction in the adult cat flea, Ctenocephalides felis (Bouché). Both blood consumption and egg production increased in a dose-dependent manner up to a maximum at 1,250 ppm when fleas were continuously exposed to concentrations up to 12,500 ppm juvenile hormone. Histological studies(More)
The effects of recombinant human interleukin-4 (IL-4) on the production of interleukin-1 (IL-1) and tumour necrosis factor-alpha (TNF alpha) by human alveolar macrophages (AM) and autologous peripheral blood monocytes (PBM) in response to lipopolysaccharide (LPS) were examined. AM and PBM were obtained by bronchoalveolar lavage and centrifugal elutriation,(More)
The activity of pyriproxyfen in the blood diet was investigated for its efficacy against adult, egg, and larval stages of the cat flea, Ctenocephalides felis (Bouché). Adult fleas were housed in plastic cages and fed treated bovine blood using an artificial membrane system that allows fleas to feed ad libitum through a parafilm membrane. Control fleas(More)
lnterleukin-4 as a potent down-regulator for human alveolar macrophages capable of producing tumour necrosis factor-a and interleukin-1. S. Sone, H. Yanagawa, Y. Nishioka, E. Orino, G. Bhaskaran, A. Ni~ K. Mizuno, Y. Heike, F. Ogush~ T. Ogura. ABSTRACT: The effects of recomblnant human lnterleukln-4 (IL-4) on the produc· tlon of lnterleuldn·l (IL-l) and(More)
Performance model solvers and simulation engines have been around for more than two decades. Yet, performance modeling has not received wide acceptance in the software industry, unlike pervasion of modeling and simulation tools in other industries. This paper explores underlying causes and looks at challenges that need to be overcome to increase utility of(More)
The effect of interleukin-4 (IL-4) on the activation state of human alveolar macrophages (AMs) and blood monocytes induced by lipopolysaccharide (LPS) or recombinant interferon-gamma (IFN-gamma) was investigated on the basis of their ability to produce superoxide anion (O2-). AMs were obtained from healthy donors by bronchoalveolar lavage, and O2-(More)
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