Gonzalo Muyo

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We describe the mapping of the optical transfer function (OTF) of an incoherent imaging system into a geometrical representation. We show that for defocused traditional and wavefront-coded systems the OTF can be represented as a generalized Cornu spiral. This representation provides a physical insight into the way in which wavefront coding can increase the(More)
INTRODUCTION The work described here involved the use of a modified fundus camera to obtain sequential hyperspectral images of the retina in 14 normal volunteers and in 1 illustrative patient with a retinal vascular occlusion. METHODS The paper describes analysis techniques, which allow oximetry within retinal vessels; these results are presented as(More)
PURPOSE To assess the accuracy of human blood oximetry measurements in a model eye with a hyperspectral fundus camera. METHODS Seven human whole blood samples (two arterial, five venous) were obtained, the oxygen saturations measured with a CO oximeter, and the samples inserted into quartz tubes with internal diameters of 100 and 150 μm. The tubes (n =(More)
A quartic phase retardation function is described that reduces the variation of the intensity of the focal point of incoherent imaging systems suffering from primary third-order aberrations limited to coma and astigmatism. Corresponding modulation transfer functions are shown to remain practically invariant for moderate amounts of coma and astigmatism.
The design of modern imaging systems is intricately concerned with the control of optical aberrations in systems that can be manufactured at acceptable cost and with acceptable manufacturing tolerances. Traditionally this involves a multiparameter optimisation of the lens optics to achieve acceptable image quality at the detector. There is increasing(More)
We demonstrate an experimental method to obtain a continuously variable hybrid imaging system that uses two generalized cubic phase masks, to enable real-time optimization of the trade between extended depth-of-field and noise gain. We obtain point-spread functions as a function of the rotation angle and show an example of optimization based on recovered(More)
A Monte Carlo simulation of light propagation through the retina has been developed to understand the path-length distributions within the retinal vessel. For full-field illumination, the path-length distribution within the vessel comprises directly backscattered light and light that has passed once or twice through the vessel. The origins of these light(More)