Gongqiang Yuan

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The purpose was to evaluate the efficacy of the intravitreal implantation of the biodegradable cyclosporin A (CsA) drug delivery system (DDS) for experimental chronic uveitis. The DDS was prepared by formulating CsA into glycolide-co-lactide-co-caprolactone copolymer (PGLC). Right eyes of 30 New Zealand white rabbits were used to establish a model of(More)
Macrophages play an important role in the pathogenesis of proliferative vitreoretinopathy (PVR). M2 macrophages can promote tissue remodeling and repair. In this study, CD206 positive M2 type macrophages were found in preretinal fibrous membranes of the mouse model of PVR induced by the intravitreal injection of retinal pigment epithelial (RPE) cells. Notch(More)
The most common pathogenic germs of mycotic endophthalmitis are Candida, Fusarium and Aspergillus fumigatus. As a dematiaceous fungus, Phialophora verrucosa (Medlar, 1915) has not been reported to cause endophthalmitis. Herein, we report a case of endophthalmitis induced by P. verrucosa and Streptococcus intermedius.
OBJECTIVE To evaluate the methods and effects of surgery for traumatic suprachoroidal hemorrhage (SH). METHODS Seventeen cases with SH caused by ocular rupture underwent secondary surgery. With BSS irrigating into vitreous cavity, we drained SH through pars plana incisions and performed routine vitrectomy with gas or silicone oil tamponade. RESULTS SH(More)
Elevated Notch signaling has been verified in a large range of fibrotic diseases developed in the kidney, liver, and lung, inducing the development of the epithelial–mesenchymal transition (EMT). The aim of this study was to observe the involvement of Notch signaling in the EMT of retinal pigment epithelial (RPE) cells and the pathogenesis of proliferative(More)
UNLABELLED We describe a modified technique of black diaphragm intraocular lens (IOL) implantation in eyes with traumatic aniridia, aphakia, and previous vitrectomy. During black diaphragm IOL implantation, a double-armed 10-0 polypropylene suture is used to fixate the IOL in the ciliary sulcus. Two 10-0 polypropylene sutures are subsequently placed in(More)
Objective To evaluate the etiologies for dense vitreous hemorrhage in adults with non-traumatic and reveal management of early vitrectomy for the disease. Methods Study included 105 eyes from 105 patients. Outcome measures were etiologies of vitreous hemorrhage, formation of retinal and/or disk neovascular membrane (NVM), incidence of retinal tear and(More)
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