Learn More
We conducted a cross-sectional study to evaluate the interrelationships between past arsenic exposure, biomarkers specific for susceptibility to arsenic exposure, and carotid intima-media thickness (cIMT) in 959 subjects from the Health Effects of Arsenic Longitudinal Study in Bangladesh. We measured cIMT levels on average 7.2 years after baseline during(More)
BACKGROUND Millions of people worldwide are chronically exposed to arsenic through drinking water, including 35-77 million people in Bangladesh. The association between arsenic exposure and mortality rate has not been prospectively investigated by use of individual-level data. We therefore prospectively assessed whether chronic and recent changes in arsenic(More)
OBJECTIVE To evaluate the association between arsenic exposure and mortality from cardiovascular disease and to assess whether cigarette smoking influences the association. DESIGN Prospective cohort study with arsenic exposure measured in drinking water from wells and urine. SETTING General population in Araihazar, Bangladesh. PARTICIPANTS 11,746 men(More)
BACKGROUND Few prospective studies have evaluated the influence of arsenic methylation capacity on cardiovascular disease (CVD) risk. OBJECTIVE We evaluated the association of arsenic exposure from drinking water and arsenic methylation capacity with CVD risk. METHOD We conducted a case-cohort study of 369 incident fatal and nonfatal cases of CVD,(More)
An updated and expanded version of the Carbon Bond mechanism (CB05) has been incorporated into the Community Multiscale Air Quality (CMAQ) modeling system to more accurately simulate wintertime, pristine, and high-altitude situations. The CB05 mechanism has nearly 2 times the number of reactions relative to the previous version of the Carbon Bond mechanism(More)
A three-dimensional air quality model is used to examine the magnitude and spatial distribution of differences in predictions among three chemical mechanisms that are used for regulatory and research modeling. The Carbon Bond mechanism CB05 is compared to an earlier version, CB4, to assess how much changes due to an update might potentially affect previous(More)
BACKGROUND Limited data are available on smoking-related mortality in low-income countries, where both chronic disease burden and prevalence of smoking are increasing. METHODS Using data on 20,033 individuals in the Health Effects of Arsenic Longitudinal Study (HEALS) in Bangladesh, we prospectively evaluated the association between tobacco smoking and(More)
OBJECTIVE Limited studies suggest that blood pressure variability over time is a risk factor of long-term cardiovascular outcomes. However, most of these were in populations with pre-existing cardiovascular diseases (CVD) and studies in general population are lacking. METHODS The study included 11,153 participants in a population-based, prospective cohort(More)
Elevated concentrations of arsenic in groundwater pose a public health threat to millions of people worldwide. The authors aimed to evaluate the association between arsenic exposure and skin lesion incidence among participants in the Health Effects of Arsenic Longitudinal Study (HEALS). The analyses used data on 10,182 adults free of skin lesions at(More)