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We conducted a cross-sectional study to evaluate the interrelationships between past arsenic exposure, biomarkers specific for susceptibility to arsenic exposure, and carotid intima-media thickness (cIMT) in 959 subjects from the Health Effects of Arsenic Longitudinal Study in Bangladesh. We measured cIMT levels on average 7.2 years after baseline during(More)
This study examines ozone (O 3) predictions from the Community Multiscale Air Quality (CMAQ) model version 4.5 and discusses potential factors influencing the model results. Daily maximum 8-h average O 3 levels are largely underpredicted when observed O 3 levels are above 85 ppb and overpredicted when they are below 35 ppb. Using a clustering approach,(More)
OBJECTIVE To evaluate the association between arsenic exposure and mortality from cardiovascular disease and to assess whether cigarette smoking influences the association. DESIGN Prospective cohort study with arsenic exposure measured in drinking water from wells and urine. SETTING General population in Araihazar, Bangladesh. PARTICIPANTS 11,746 men(More)
BACKGROUND Few prospective studies have evaluated the influence of arsenic methylation capacity on cardiovascular disease (CVD) risk. OBJECTIVE We evaluated the association of arsenic exposure from drinking water and arsenic methylation capacity with CVD risk. METHOD We conducted a case-cohort study of 369 incident fatal and nonfatal cases of CVD,(More)
A three-dimensional air quality model is used to examine the magnitude and spatial distribution of differences in predictions among three chemical mechanisms that are used for regulatory and research modeling. The Carbon Bond mechanism CB05 is compared to an earlier version, CB4, to assess how much changes due to an update might potentially affect previous(More)
BACKGROUND Limited data are available on smoking-related mortality in low-income countries, where both chronic disease burden and prevalence of smoking are increasing. METHODS Using data on 20,033 individuals in the Health Effects of Arsenic Longitudinal Study (HEALS) in Bangladesh, we prospectively evaluated the association between tobacco smoking and(More)
Preterm and term transitional milks of human subjects and mature milks of human subjects, non-human primates and non-primates were analysed for free amino acids (AA) using precolumn phenylisothiocyanate derivatization and liquid chromatography. Differences in free AA between three types of human milk were small. Milks of pinnipeds (seals and sea lions)(More)
Predictions of nitrous acid from the Community Multiscale Air Quality modeling system are compared with the measurements from the 2001 Northeast Oxidant and Particle Study. Four different sources of nitrous acid were considered in the study: gas-phase reactions, direct emissions, a heterogeneous reaction, and a surface photolysis reaction. When only(More)
This paper presents model estimates of the effect of chlorine emissions on atmospheric ozone concentrations in the eastern United States. The model included anthropogenic molecular chlorine emissions, anthropogenic hypochlorous acid emissions from cooling towers and swimming pools, and chlorine released from sea-salt aerosols. The release of chlorine(More)